:: Medicina
Bibliografia/References
Francisco Mora, Luigi Francesco Agnati, Kjell Gunnar Fuxe
 

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6 Agnati, L.F., Santarossa, L., Genedani, S., Canela, E.I., Leo, G., Franco, R., Woods, A., Lluis, C., Ferrè, S. and Fuxe, K. (2004) On the nested hierarchical organization of CNS: basic characteristics of neuronal molecular networks. In: Computational Neuroscience: cortical dynamycs, Lecture Notes in Computer Sciences, Erdi P., Esposito A., Marinaro M., Scarpetta S., (Eds.), Springer, Berlin Heidelberg New York , pp. 24-54.
7 Agnati, L.F., Tarakanov, A.O., Ferrè, S. and Fuxe, K. (2005) Receptor-receptor interactions,receptor mosaics, and basic principles of molecular network organization: possibile implications for drug development. J. Mol. Neurosci. 26: 193-208.
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20 Yerbury, J.J., Stewart, E.M., Wyatt, A.R. and Wilson, M.R. (2005) Quality control of protein folding in extracellular space. EMBO, 6: 1131-6.
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22 Agnati, L.F., Santarossa, L., Benfenati, F., Ferri, M., Morpurgo, A., Apolloni, B. and Fuxe, K. (2002) Molecular basis of learning and memory: modelling based on receptor mosaics. In From Synapses to Rules, (eds B. Apolloni and F. Kurfes), Kluwer Academic/Plenum Publishers, New York, pp. 165-96.
23 Agnati, L.F., Ferrè, S., Lluis, C., Franco, R. and Fuxe, K. (2003) Molecular Mechanisms and therapeutical implications of intramembrane receptor/receptor interactions among heptahelical receptors with examples from the striatopallidal GABA neurons. Pharmacol. Rev. 55: 509-50.
24 Agnati, L.F., Guidolin, D., Genedani, S., Ferré, S., Bigiani, A., Woods, A.S. and Fuxe, K. (2005) How proteins come together in the plasma membrane and function in macromolecular assemblies: focus on receptor mosaics. J. Mol. Neurosci. 26: 133-54.
25 Agnati, L.F., Leo, G., Zanardi, A., Genedani, S., Rivera, A., Fuxe, K. and Guidolin, D. (2006) Volume transmission and wiring transmission from cellular to molecular networks: history and perspectives. Acta Physiol. 187: 329-44.
26 Agnati L.F. (2006) Testo Atlante di Fisiologia Umana: Apparato Renale. CEA, Milano.
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30 Koshland, D.E. Jr and Hamadani, K. (2002) Proteomics and models for enzyme cooperativity. J. Biol. Chem. 277:46841-4.
31 Agnati, L.F., Fuxe, K. and Ferrè S. (2005) How receptor mosaics decode transmitter signals. Possible relevance of cooperativity. Trends Biochem. Sci. 30: 188-93.
32 Agnat,i L.F., Fuxe, K., Zoli, M., Rondanini, C. and Ögren, S.O. (1982) New vistas on synaptic plasticity: the receptor mosaic hypothesis of the engram. Med. Biol. 60:183-190.
33 Agnati, L.F., Ferré, S., Leo, G., Lluis, C., Canela, E.I., Franco, R. and Fuxe K. (2004) On the Molecular Basis of the Receptor Mosaic Hypothesis of the Engram
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34 Agnati, L.F., Franzen, O., Ferré, S., Leo, G., Franco, R. and Fuxe, K. (2003) Possibile role of intramembrane receptor-receptor interactions in memory and learning via formation of long-lived heteromeric complexes: focus on motor learning in the basal ganglia. J. Neural. Transm. 65:195-222.
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38 Selkoe, D.J. (2003) Aging, amyloid and Alzheimer's disease: A perspective in honor of Carl Cotman. Neurochem. Res. 28:1705-13.
39 Lee, H.G., Castellani, R.J., Zhu, X., Perry, G. and Smith, M.A. (2005) Amyloid-? in Alzheimer's disease: the horse or the cart? Pathogenetic or protective? Int. J. Exp. Path. 86:133-8.
40 Gong, Y., Chang, L., Viola, K.L., Lacor, P.N., Lambert, M.P., Finch, C.E., Krafft, G.A. and Klein, W.L. (2003) Alzheimer's disease-affected brain: Presence of oligomeric A_ ligands (ADDLs) suggests a molecular basis for reversible memory loss. Proc. Natl. Acad. Sci. USA 100:10417-22.
41 Lacor, P.N., Buniel, M.C., Chang, L., Fernandez, S.J., Gong, Y., Viola, K.L., Lambert, M.P., Velasco, P.T. et al. (2004) Synaptic Targeting by Alzheimer's-Related Amyloid Oligomers. J. Neurosci. 24: 10191-200.
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43 Stephan, A., Laroche, S. and Davis, S. (2001) Generation of aggregated -amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits. J. Neurosci. 21: 5703-14.
44 Foguel, D. and Silva, J.L. (2004) New insights into the mechanisms of protein misfolding and aggregation in amyloidogenic diseases derived from pressure studies. Biochemistry 43(36): 11361-11370.
45 Seshadri, S., Beiser, A., Selhub, J., Jacques, P.F., Rosenberg, I.H., D'Agostino, R.B., Wilson, P.W. and Wolf, P.A. (2002) Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N. Engl. J. Med. 346(7): 476-83.
46 Ho, P.I., Collins, S.C., Dhitavat, S., Ortiz, D., Ashline, D., Rogers, E. and Shea, T.B. (2001) Homocysteine potentiates beta-amyloid neurotoxicity: role of oxidative stress. J. Neurochem. 78(2): 249-53.
47 Prusiner, S.B. (1997) Prion Diseases and the BSE Crisis. Science 278: 245-51.
48 Prusiner, S.B. (1998) Prions. Proc. Natl. Acad. Sci. U. S. A. 95(23),13363-13383
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52 DeMarco, M.L. and Daggett, V. (2005) Local environmental effects on the structure of the prion protein. C R Biologies 328:847-62.
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59 Agnati, L.F., Zunarelli, E., Genedani, S. and Fuxe, K. (2006) On the existence of a global molecular network enmeshing the whole central nervous system: physiological and pathological implications. Curr. Protein. Pept. Sci. 7(1): 3-15.
60 Van Horssen, J., Wesseling, P., van den Heuvel, L.P., de Waal, R.M. and Verbeek, M.M. (2003) Heparan sulphate proteoglycans in Alzheimer's Disease and amyloid-related disorders. Lancet Neurol. 2:482-92.
61 Paratcha, G. and Ibanez, C.F. (2002) Lipid rafts and the control of neurotrophic factor signaling in the nervous system: variations on a theme. Curr. Opin. Neurobiol. 12, 542-9.
62 Eyal, A., Szargel, R., Avraham, E., Liani, E., Haskin, J., Rott, R. and Engelender, S. (2006) Synphilin-1A: An aggregation-prone isoform of synphilin-1 that causes neuronal death and is present in aggregates from -synucleinopathy patients. Proc. Natl. Acad. Sci. USA 103:5917-22.
63 Agnati, L.F., Genedani, S., Leo, G., Forni, A., Woods, A.S., Filaferro, M. and Fuxe, K. (2006) Ab peptides as one of the crucial Volume Transmission signals in the trophic units and their interactions with homocysteine. Physiological implications and relevance for Alzheimer's disease. J. Neural. Transm. In press.

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